Recently, scientists have developed a new biomaterial that can be used to disinfect wounds and hastens the process of healing, as seen in mouse models.
About Aureobasidium pullulans
- Aureobasidium pullulans is a ubiquitous and generalistic black, yeast-like fungus that can be found in different environments (e.g. soil, water, air and limestone).
- It is well known as a naturally occurring epiphyte or endophyte of a wide range of plant species (e.g. apple, grape, cucumber, green beans, cabbage) without causing any symptoms of disease.
- The biomaterial is derived from the polymer pullulan which is secreted by the fungus Aureobasidium pullulans .
- It is an exopolysaccharide, that is, this polymer is secreted by the fungus itself into the medium on which it is growing.
- Pullulan as a biomaterial is already successful and widely used commercially.
- It is exploited in food, cosmetics and pharmaceutical industry because of its non-toxic, non-mutagenic and non-immunogenic properties.
- Further, its ease of manufacture has also added to its appeal.
- In the biomedicine sector, it has been used for drug and gene delivery, its use as a antimicrobial biomaterial had not been explored.
- Pullulan is basically a polymeric chain of glucose.
- They process the polymer to get a powder which is water-soluble. This solution can be applied on the wound surface and then covered with a sterile gauze. This can also be used in a gel form.
- This is because hydrogels have an inherent ability to accelerate wound healing by providing a closed and moist environment to the wounds for easy exchange of oxygen and act as absorbent pad to remove the pus and debris.
Visit Abhiyan PEDIA (One of the Most Followed / Recommended) for UPSC Revisions: Click Here
IAS Abhiyan is now on Telegram: Click on the Below link to Join our Channels to stay Updated
IAS Abhiyan Official: Click Here to Join
For UPSC Mains Value Edition (Facts, Quotes, Best Practices, Case Studies): Click Here to Join