Aureobasidium pullulans

Aureobasidium pullulans


  • Recently, scientists have developed a new biomaterial that can be used to disinfect wounds and hastens the process of healing, as seen in mouse models.

About Aureobasidium pullulans

  • Aureobasidium pullulans is a ubiquitous and generalistic black, yeast-like fungus that can be found in different environments (e.g. soil, water, air and limestone).
  • It is well known as a naturally occurring epiphyte or endophyte of a wide range of plant species (e.g. apple, grape, cucumber, green beans, cabbage) without causing any symptoms of disease.
  • The biomaterial is derived from the polymer pullulan which is secreted by the fungus Aureobasidium pullulans .
  • It is an exopolysaccharide, that is, this polymer is secreted by the fungus itself into the medium on which it is growing.
  • Pullulan as a biomaterial is already successful and widely used commercially. Aureobasidium pullulans - Wikipedia
  • It is exploited in food, cosmetics and pharmaceutical industry because of its non-toxic, non-mutagenic and non-immunogenic properties.
  • Further, its ease of manufacture has also added to its appeal.
  • In the biomedicine sector, it has been used for drug and gene delivery, its use as a antimicrobial biomaterial had not been explored.
  • Pullulan is basically a polymeric chain of glucose.
  • They process the polymer to get a powder which is water-soluble. This solution can be applied on the wound surface and then covered with a sterile gauze. This can also be used in a gel form.
  • This is because hydrogels have an inherent ability to accelerate wound healing by providing a closed and moist environment to the wounds for easy exchange of oxygen and act as absorbent pad to remove the pus and debris.


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