Mid-life Obesity

  • A team of scientists has identified an enzyme that could help in the continuous battle against mid-life obesity and fitness loss.
  • The discovery in mice could upend current notions about why people gain weight as they age, and could one day lead to more effective weight-loss medications.
  • The study, the first to link the increased activity of this enzyme to aging and obesity, appears in the current issue of Cell Metabolism.
  • Its findings could have ramifications for several chronic illnesses.
  • With lower rates of obesity, the researchers say, rates of heart disease, diabetes, and other diseases that tend to increase with age, including cancer and Alzheimer’s disease, could fall as well.
  • The study opens the door to the development of a new type of weight-loss medication that could work by inhibiting DNA-PK activity.



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